Top 32 fantasy football D/STs for Week 15

Dec 10, 2025 - 12:00
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Top 32 fantasy football D/STs for Week 15

Welcome to the fantasy football playoffs! Like most years, the fantasy playoffs come at the same time quarterbacks have worn down and backups are taking over or, they’re just playing out the season with what they have lying about. That’s good news for D/STs. Brady Cook? Riley Leonard? Phillip Rivers (grandfather version), Kirk Cousins (grandfather version), Tyler Shough, Kenny Pickett, Cam Ward? They all make for good quarterbacks to target with whatever defense they’re going up against.

Week 15 byes

None.

D/ST streamer of the week

Jacksonville Jaguars D/ST vs Jets

The Jaguars D/ST has been putting together decent numbers of late, with double-digit fantasy points in four of their last five games. Now they face a Jets team at home as 11.5-point favorites. The Jets could be on their third-string quarterback this week as well. Grab the Jags and do the thing.

Week 15 odds

Highest point totals

Lions at Rams (54.5)
Ravens at Bengals (51.5)
Bills at Patriots (49.5)
Vikings at Cowboys (47.5)

Lowest point totals

Raiders at Eagles (38.5)
Browns at Bears (40.5)
Panthers at Saints (40.5)
Jets at Jaguars (41.5)

Highest implied individual team totals

Rams (30)
49ers (28.5)
Seahawks (28)
Cowboys (27)
Ravens (27)

Lowest implied individual team totals

Raiders (13.5)
Colts (14.5)
Jets (15)
Titans (16)

Largest point spreads

Colts at Seahawks (-13.5)
Titans at 49ers (-12.5)
Raiders at Eagles (-11.5)
Jets at jaguars (-11.5)
Cardinals at Texans (-9.5)

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